Research

Research Focus

This research on the brain and potentially on the spinal cord concerns people who have an exclusive motor disability acquired by an accident or at birth. Rather young people who have a normal or even superior intellectual function but who are prisoners of their bodies. We know the cause of the disease and we do not yet know exactly where to intervene on the network to control this overload of muscular activity. There are no lost functions, everything is disorganized until there is a total loss of autonomy. Today the rate of improvement is too low and the objective of our research is to improve the treatment of dystonias.

Our laboratory specializes in the in-depth study of abnormal movements. We collaborate with academic institutions, healthcare organizations, and technology companies to push the boundaries of what we know about these complex disorders.

Our projects include studies of genomics, neurons, human-machine interfaces, deep brain stimulation and the development of innovative diagnostic tools using artificial intelligence and advanced imaging techniques.

What We Study

Forms of dystonia

Dystonia

Dystonia is a neurological disorder characterized by involuntary muscle contractions, causing repetitive or twisting movements, and abnormal postures. These symptoms can vary in severity and extent, affecting one part of the body or all of it. Despite existing treatments, dystonia remains a significant challenge, requiring extensive research to better understand its causes

Anoxic Dystonia

Particularly complex, anoxic dystonia results from oxygen deprivation in the brain, mainly affecting the basal ganglia, essential for motor control. This type of dystonia can occur as a result of a variety of incidents, such as narrowly avoided drowning or cardiac arrest. Treatment options are limited and there is an urgent need for research to offer better management strategies and potentially curative treatments.

Themes

Innovations at the servic of research

This phase is devoted to the development of innovative treatments integrating cutting-edge technologies.

We will launch phase 1 clinical trials to test the safety and effectiveness of new stimulation approaches. We will also develop integrated treatment models, combining neurostimulation, pharmacology and behavioral therapies, adapted to individual patient profiles.

Our focus is on the refinement of diagnostic tools. We integrate artificial intelligence to develop algorithms capable of assessing and diagnosing dystonia, and improving treatment outcomes.

New imaging techniques will be exploited to detect subtle changes in the brain and spinal cord, specific to anoxic dystonia.

Resources

Innovations at the servic of research

This phase is devoted to the development of innovative treatments integrating cutting-edge technologies.

We will launch phase 1 clinical trials to test the safety and effectiveness of new stimulation approaches. We will also develop integrated treatment models, combining neurostimulation, pharmacology and behavioral therapies, adapted to individual patient profiles.

Our focus is on the refinement of diagnostic tools. We integrate artificial intelligence to develop algorithms capable of assessing and diagnosing dystonia, and improving treatment outcomes.

New imaging techniques will be exploited to detect subtle changes in the brain and spinal cord, specific to anoxic dystonia.